The fire was lit between midnight and 5am when emergency services responded and found the house fully engulfed.

Detective Sergeant Calum McCann from Macedon Range Crime Investigation said the front of the house was destroyed.

"A 36-year-old female has been charged in relation to (the fire) and is before the court," he said.

"The offender suffered smoke inhalation and was treated at the scene.

"She was arrested at the scene and will face Kyneton Magistrates Court."

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