A man in his 20s was flown by air ambulance to hospital in Melbourne with injuries to his back and ankle after a crash on the Bendigo-Maryborough Road on Friday.

The man was in a stable condition.

Two women in their 20s were taken by road ambulance to Bendigo Hospital, both in a stable condition.

A man in his 20s was taken to Bendigo Health Centre in a stable condition.

Friday, 3.30pm:

A woman in her 20s will be flown by air ambulance to hospital after a two-car crash on the Bendigo-Maryborough Road at Woodstock at 2.40pm on Friday.

One of the cars rolled following the collision, with an occupant having to be cut out by the Country Fire Authority.

The woman, who had leg injuries, was in a stable condition, a spokesperson for the ambulance service said.

A man with back injuries, who was also stable, was taken by road ambulance to hospital.

Two other people were being assessed at the scene but were not believed to be injured, the spokesperson said.

Police have closed off the road.

Earlier: A man and woman are believed to have been involved in a car crash on the Bendigo-Maryborough Rd, near Shelbourne.

The Country Fire Authority has four trucks on the site of a two car crash. Ambulance, police and SES are also at the scene.

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