Cancer Council Victoria is reminding parents of boys in year nine to have their final free HPV vaccination.
HPV, or human papilloma virus, is a common sexually transmitted infection.
Cancer Council prevention division director Craig Sinclair said HPV was usually harmless but if left undetected, could cause cancer.
Mr Sinclair said the HPV vaccine can significantly decrease a male's chances of developing HPV-related illnesses which include cancer later in life and genital warts.
The vaccine is available for free until the end of this year.
It is given at school and aims to prevent 90 per cent of all HPV-related cancers in men.