UPDATE, 6PM SATURDAY: A witness has told police that three cars were travelling erratically side-by-side when a fatal crash occurred near Wedderburn.
Detective Senior Sergeant Gerard Clanchy from the Major Collision Investigation Unit urged more witnesses to the crash to come forward.
“We need to get to the bottom of what happened,” he said.
“This is something that shouldn’t happen. Two people have lost their lives through driving that is just unacceptable.”
Detective Senior Sergeant Clanchy said it appeared two of the vehicles had collided and ran off the Calder Highway into trees on Saturday afternoon.
A 51-year-old Wedderburn man who was travelling in the third car is at Bendigo Police Station assisting police.
A 35-year-old woman was flown to the Royal Melbourne Hospital and a 67-year-old man is at Bendigo Hospital.
The two deceased people were adult males, believed to be from the local area.
TWO people are under police guard in hospital following a double fatality near Wedderburn this afternoon.
Police have confirmed two people have died and two others remain in a serious condition following the two-car collision at Glenalbyn.
Sergeant Peter Beaman said the vehicles were travelling south along the Calder Highway at about 12.40pm today when the collision occurred.
Ambulance Victoria spokesman John Mullen said a woman in her thirties had been transported to the Royal Melbourne Hospital with head injuries, and a man in his forties had been transported to Bendigo Health.
They are under police guard and remain in a serious but stable condition.
A crime scene has been set up and the highway will be blocked in both directions while the Major Crash Unit work to establish the circumstances surrounding the collision.
"Police are investigating the circumstances of the crash," a spokesperson said.
Police could not confirm the age or sex of the deceased.
More to come...