The changes come as Premier Daniel Andrews confirmed Victoria's lockdown would end at midnight.

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Bendigo Senior Secondary College principal Dale Pearce said the whole school community was pleased with the announcement.

"Students as well as teachers and probably parents have been very happy to see students return to school tomorrow," he said.

"Just like everybody, we have been following the daily updates and numbers and so it wasn't a surprise that we would be back this week but it was amazing to get that confirmation."

Mr Pearce said mask wearing would perhaps be "the most significant change" for students.

"It will be a change from where we were previously (post July lockdown), students will now be made to wear masks indoors and outdoors," he said.

"I think students will manage that well and we have been accustomed to doing that over the past couple of weeks.

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"It's a change from what we were previously doing at school but it is consistent with the expectations outside of school so I would expect students will cope with that well."

Mr Pearce said there had been many challenges brought forward during the past lockdown for students.

"This is the fifth time the students have been through remote learning," he said.

"There has been a particular challenge with the Year 12 students given they had the interruptions throughout 2020 and again this year.

"The anxiety amongst that group of students has been reasonably high."

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Mr Pearce said another challenge has been students missing face-to-face interactions.

"Another thing to note is the longer these periods of remote learning go, the more difficult it becomes for students who lose contact with their peers, teachers," he said.

"It is such an important part of the school experience."

Marist College Bendigo principal Darren McGregor said all teachers and staff were excited and looking forward to the return of face-to-face learning.

"It will be really great to have all of our students back to face-to-face learning from tomorrow," he said.

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"We were a little concerned earlier today when there was a talk about a staggered return of schools, with some being a school and some at home but we are very pleased that wasn't the case and everyone will be back together."

Mr McGregor said there may be some anxiety around the return for not only students but teachers and staff.

"We are all so conscious of the anxiety that will be there particularly for staff as a lot of workplaces are having 25 per cent back, we have everyone back and I think all of our teachers are doing a brilliant job to be at the frontline of this," he said.

"The learning from home was an added strain on staff and we will all work through those anxieties and continue to work with staff."

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