Ambulance Victoria has confirmed three people were taken to Bendigo Health following a collision in Epsom at around 2.30pm on Tuesday.
A spokesperson said a man believed to be in his 30s suffered hip pain and lacerations and was taken to hospital in a serious condition.
Another man, believed to be in his 50s, suffered a foot injury and was taken to Bendigo Health in a stable condition.
A woman believed to be in her 40s suffered neck pain and was taken to hospital, also in a stable condition.
Bendigo Sergeant Mick McCrann said the two-car crash at Epsom happened when the driver of a black ute crossed onto the opposite side of Howard Street and hit an oncoming white Mitsubishi.
"At this stage, one vehicle is on the incorrect side of the road," he said.
"The evidence is clear and we have a witness attesting to that. So obviously there is some fault on that driver and we will be following that up."
Sergeant McCrann said the male driver of the black ute, 32, suffered leg injuries. An ambulance took him to Bendigo hospital for treatment.
The 55-year-old male and 46-year-old female, both of Huntly, were also injured and treated by paramedics at the scene.
"At one stage we had SES, fire, police and ambulance on scene," Sergeant McCrann said.
"We needed some assistance in getting people out of the vehicles, so they were trapped for a little while."
Police are investigating the incident.
"We would appeal to any witnesses who may have seen the incident occur to contact police or highway patrol at Bendigo," Sergeant McCrann said.
Tow trucks have now removed the cars from the scene and police and the Country Fire Authority is preparing to reopen Howard Street.
THREE people have been taken to hospital following a two-car crash in Epsom.
An Ambulance Victoria spokesperson confirmed the patients had been transported to Bendigo Health.
The spokesperson was unable to confirm their injuries or conditions.
EMERGENCY services are responding to a two-car crash in Epsom.
Fire crews, police, and paramedics were called to the collision on Howard Street about 2.36pm on Tuesday.
An Ambulance Victoria spokesperson confirmed paramedics were assessing three people at the scene.
The three people - a man and woman believed to be in their 50s, and a man believed to be in his 30s - do not have life-threatening injuries.
There are reports the two people in their 50s are mechanically trapped in their vehicle.
Police are blocking traffic on Howard Street in both directions.
More to come
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