More than 10,000 properties in the Macedon Ranges remained without power on Friday morning, the region's electricity provider confirmed.
SES and power crews are continuing the clean up after wild storms hit the state on Wednesday night.
The Kyneton district was among the hardest hit by damaging winds, although the region escaped the flooding rain that drenched Gippsland.
Trentham is also the focus of clean-up efforts and the town is suffering from water supply problems.
Powercor said on Friday morning that close to 11,000 properties in the Kyneton, Woodend, Trentham and Gisborne areas.
"Much of the major repair work is being conducted in areas that were unable to be accessed yesterday due to dangerous conditions, large fallen trees and other debris. Dedicated vegetation teams were needed to cut and remove trees to allow access," a Powercor spokesperson said.
"We are still assessing some of the damage in Trentham as we have had difficulties accessing some parts of our network, and are working closely with emergency services in the area.
"We expect to restore power to the majority of customers by late today, however some customers will still be without power into the weekend. These customers are likely to be single premise faults, where service wires have been brought down.
"We know our customers are doing it tough in these conditions without power and we want to assure customers that we are doing everything to get power back on as safely and as quickly as possible."
Powercor urged people to remain patient and calm, saying a small number of customers had been abusive towards crews.
Acting premier James Merlino thanked those working around the clock to clean up the state.
"It is not over yet," Mr Merlino said.
He said there had been 7400 requests for help from the SES, and there were 121,000 homes without power.
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