It is part of the bank's push beyond conventional ideas about branches to stay relevant to customers, the Bendigo Bank's state manager Justine Minne said.

"It's a change that's very much driven by our customers. When it comes to banking and finance we've seen a rise in people interacting very differently with us, whether that be through self-service or digital banking," she said.

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The shift has prompted the bank to rethink its Mitchell Street branch's layout and explore ways to help meet people's needs in a welcoming environment.

Mitchell Street will be the first of the bank's "heartland" branches to use the new model after the concept was honed in other areas, Ms Minne said.

She said people would immediately notice a difference when they arrive at the branch.

They will see a retail pop-up space that showcasing a different local business or creatives' work every two weeks.

They will also see an art gallery space and be able to hire space for meetings, workshops and smaller events.

The branch has also been designed to make it easier for people to access experts and technology.

Australia's banking industry is seeing a long-term decline in branch numbers.

Bendigo Bank itself closed its White Hills branch earlier this year, citing falling customer interactions as younger people embraced online banking.

Ms Minne said branches will keep playing a central role in the bank's operations, particularly for important moments in people's lives and businesses.

"They will always be required because people want that face-to-face presence when they want to solve a problem, achieve a life goal or make a big transaction," she said.

Ms Minne added that something else will never change. The Mitchell Street branch will still sport a clock and temperature gauge.

"The feedback from people was that the clock absolutely had to stay," Ms Minne said.

It will likely be reinstalled outside the building in early December, she said.