BENDIGO'S Scots Day Out has become the pandemic's latest scalp.
The 2021 event is being canceled over uncertainty about future COVID-19 restrictions.
Event director Chris Earl said organisers had been in extensive discussions with the City of Greater Bendigo about hosting the event next February.
"However, without event guidelines from government for major regional events nor any indications of allowed participant and spectator numbers, there is an absence of a practical framework with surety for planning SDO 2021," he said in a statement on Friday afternoon.
Mr Earl noted that pipe bands - a centre-piece of the event - had not been able to practice since social restrictions began in March.
"Public performances into the foreseeable are not possible under current and projected restrictions, including the wearing of face masks," he said.
"Other pipe band competitions and highland gatherings through until next March have already been cancelled."
Mr Earl acknoledged the decision would affect many including stall holders who often travel from interstate and who were enthusiastic supporters of Bendigo's event.
"We regret that our ninth running of Scots Day will not be possible in 2021," he said.
"It has been a difficult decision and we thank City of Greater Bendigo for its ongoing support of SDO and willingness to investigate venue options.
"Events like Scots Day Out are important community showpieces across regional Victoria and their absence from the regional event calendar is leaving a gaping link in our hopes for a return to social connection and cohesion that will be essential in the rebuilding and recovery journey for local economies, communities, organisations and people."