A 53-year-old Nyah West man was killed when his prime mover and trailer came off the highway and rolled down the embankment near Fentons Lane in Ravenswood on April 29, 2019.

A coronial investigation heard a motorist travelling behind the truck saw it cross the centre line of the highway as it approached right-hand bend, the tyres on the right side come off the ground and smoke come off the left-side tyres.

The truck tracked left before slipping down the embankment and rolling.

One of the police officers who attended the crash, Senior Constable Paul Schroeder, said he believed straightening that section of the road to remove this bend, and a left-hand bend before it, was the best option for improving safety.

"At a minimum the addition of speed advisory signs and roadside physical barriers would assist light and heavy vehicles with negotiating the section of the road and minimise the chance of a vehicle leaving the roadway and rolling down the embankment," Senior Constable Schroeder said in a statement.

Coroner Darren Bracken recommended VicRoads assess the condition of that section of the Calder Alternative Highway, with input from police.

He said this assessment should look at the adequacy of signage and road safety barriers.

It was also recommended VicRoads implement any changes identified as appropriate through this assessment.

Regional Roads Victoria, a division of VicRoads, installed advisory signage on this stretch of road earlier this year, following a road safety audit.

The death of anyone on our roads is absolutely tragic and our thoughts are with anyone impacted by this loss," RRV regional director (northern) Brian Westley said.

"Following any serious crash on our roads we investigate whether any additional improvements can be made.

"We've already installed additional advisory signage and will continue to carefully consider the coroner's findings."

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In the last ten years one fatal crash and three other crashes have been recorded on the Calder Alternative Highway, within one kilometre either side of Fentons Lane.

But Mr Bracken said he was unable to determine why the truck left the road in April 2019, however he noted the cannabis found in the driver's system and a cardiovascular condition could have played a role.

There was no evidence the truck was speeding, he said, but the truck might have been travelling too fast for that bend.

"The vehicle's speed through the bend combined with road design, inappropriate placement of vehicle on the road and the high centre of gravity of the vehicle's load may have all contributed to the vehicle leaving the road," Mr Bracken said.