La Trobe University may make a further 215 to 415 involuntary redundancies even after staff voted on an agreement variation.
A university spokesperson said it could be less with more cost-savings combined with increased revenue.
"We have made it clear to staff all the way through the process that additional redundancies would be required beyond the initial voluntary redundancies round and the variation to the La Trobe Collective Agreement," the spokesperson said.
"As we will be working under the Australian Universities Job Protection Framework, no involuntary redundancies will occur in an area of the University without first opening up the option of voluntary redundancies."
La Trobe staff voted earlier this week to take a pay cut and voluntary redundancies as part of a variation of the La Trobe Collective Agreement.
The variation is pursuant to the Australian University Job Protection Framework which is designed to save $30 million in 2020 or the equivalent of about 225 jobs.
It sees some staff members would take pay cuts for one year, and redundancies would only happen in cases where a university could explicitly prove there was no work.
The potential 215 to 415 involuntary redundancies would be in addition to what staff voted for earlier in the week.
La Trobe University hopes the number can be reduced as with further savings at the university.
"After savings via the variation to La Trobe's Collective Agreement, the initial round of voluntary redundancies and other savings, based on our financial shortfall because of COVID-19, we estimate between 215 and 415 involuntary redundancies may be required," the spokesperson said.
"However, further cost-savings, combined with increased revenue, could mean this number is reduced.
"Minimising the scale and impact of any involuntary redundancies is the University's highest priority over the coming months and we will take a measured approach which supports La Trobe's reset strategy to identify where any further redundancies may be required."