Victoria Police were out in increased numbers from Thursday to Sunday night to try and combat the state's rising road death toll.

"The focus of Operation Argus was on the main factors that lead to serious injuries," Bendigo Highway Patrol Sergeant Mick McCrann said.

"So things like speed, alcohol and drugs, fatigue and distraction offences like using a mobile phone while driving.

"Behaviour generally was quite good over the weekend but we still had some disappointing things."

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Sergeant McCrann said there were extra police patrolling on the main arterial roads like the Calder Freeway, as well as key intersections in the Bendigo CBD.

At least two drivers were caught driving at excessive speeds on the Calder Highway over the weekend.

A 43-year-old driver was nabbed going almost 40 kilometres over the speed limit on the Calder near Ravenswood on Sunday morning.

The Leitchville woman was clocked travelling at 138 kilometres per hour in a 100 kilometres per hour section about 8.50am.

It followed an 84-year-old man speeding while overtaking a caravan on the Calder Freeway near Faraday on Saturday.

Police clocked his Range Rover travelling at 145 kilometres per hour in a 110 kilometres per hour zone about 10.55am.

Both drivers were fined and had their licences suspended.

Sergeant Mick McCrann said in situations where police have stopped drivers on a major highway, other motorists needed to be aware of basic road rules.

"We are highly vocal about these operations because we want people to take care on the roads," Sergeant McCrann said.

"But people need to make sure they slow down to 40 kilometres an hour when they drive past us when we've stopped someone.

"It's just about safety from our point of view. It's been legislated for a long time and we purely want to look after the welfare of our guys and girls."

A number of drivers were also nabbed in the Bendigo CBD on Sunday, with Bendigo Senior Constable Levina Bell catching two drivers who were driving while suspended within two hours.

One of the drivers, a 36-year-old female from Bendigo, also recorded a positive drug test and her vehicle was impounded at the scene.

The other driver, a 59-year-old woman from Golden Square, was found to be driving while suspended for a medical review.

Both women have been summoned to appear at the Bendigo Magistrates Court at a later date.

"People that do need to undergo medical reviews on the licence do need to follow that up," Senior Constable Bell said.

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"A lot of people are a bit naive and think if they go to the doctors then it's all ok. But it is their licence and it's their responsibility to make sure they are allowed to drive."

Senior Constable Bell said even the most unlikely offenders needed to be careful, after Bendigo police nabbed a 93-year-old Kangaroo Flat man on Tuesday who blew a blood-alcohol reading of 0.094.

The man had been driving to pick up his son from the train station after drinking an unknown amount of whiskey.

"He misjudged the corner, turned too late, mounted the nature strip and clipped a wire front fence," Senior Constable Bell.

"He was so intoxicated, he was still attempting to accelerate the car when police arrived. But it's quite sad because he's had his licence for 80 years and he's never had anything major on his criminal record.

"Because it's his first offence and he blew under 0.10, his licence was automatically disqualified and cancelled for the next six months. So he will need to go for another test to get his licence back."

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