NATIONAL suicide prevention charity R U OK? will visit Bendigo and Daylesford as part of a 14,000-kilometre educational tour.
It comes as research shows 63 per cent of Australians are not confident they know the signs someone might be struggling with life.
Forty-one per cent of the 1026 people surveyed said they hadn't asked someone if they were OK because they were uncertain.
But the research, commissioned by R U OK, found there was an appetite to learn. Almost half of the respondents said they would be more confident if they knew the signs.
"Signs can be subtle changes in verbal or non-verbal behaviour," R U OK? chief executive Katherine Newton said.
Examples included a friend or loved one experiencing unusual mood swings, changes in their sleep patterns, or withdrawing from social situations like not turning up to sport training.
"We're encouraging people to look out for those cues. We should also make a conscious effort to reach out to someone going through a significant life change such as job loss, relationship breakdown, study pressure or perhaps becoming a parent," Ms Newton said.
"This R U OK? Day we went to empower people to trust their gut instinct and ask the question as soon as they spot the signs that someone might be struggling with life."
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The Trust the Signs tour will be in Bendigo from 12pm - 1.30pm Saturday at the Bendigo Health Mercy Street carpark.
It visits Daylesford the following day from 9am - 1pm at the Daylesford Sunday Market, 18 Raglan Street.
The tour includes an educational installation, ambassador talks and activities.
More than 20 visits are scheduled as part of the tour in the lead-up to R U OK? Day on September 12.
Ms Newton said people had become more aware of R U OK? in the 10 years it had been around.
"It is no longer a question for one day, it is a question for every day," she said.
"Part of suicide prevention efforts is trying to increase the sense of social connection and belonging."
She said having an R U OK? conversation, if it was genuine and there was trust between two people, could be the support someone needed.
Ms Newton said more people were becoming willing and able to have the conversation, and more people were honestly answering the question.
"We know more people are coming to us to say, 'What do I do when someone says no?'" she said.
To register, visit ruok.org.au/trust-the-signs-tour