Senior Constable Grace MacLoy said police were still seeking assistance from the public in relation to the hold-up.

"We are asking anyone who resides in the (Williamson Street) area to check their yards and bins for items that may have been dumped there," she said.

"If anything is found they should contact Bendigo police to work out if it is related (to the crime)."

Resident with information can call Bendigo Police on 5448 1300 or Crime Stoppers on 1800 333 000.

UPDATE 2.20PM:

Police have attended the Williamson Street store. 

Two officers were seen questioning a man in the store. 

UPDATE 11.41PM: 

Bendigo police are questioning someone over the armed robbery at the Williamson Street 24-hour store.

Detective Jason Smith said the person was assisting police with their inquiries. 

EARLIER: 

POLICE are investigating an armed robbery in Bendigo.

The robbery took place in the early hours of Tuesday morning.

Police attended the Williamson Street 24-hour general store around 3am after reports of an armed robbery.

Acting Sergeant Kevin Hume-Cook said a person allegedly entered the store with a knife and demanded money.

He said the offender received money and then left the store.

“The Criminal Investigation Unit is looking into a couple of leads,” Acting Sergeant Hume-Cook said.

It is not the first time the 24-hour store has been targeted.

In August a man was arrested in dramatic fashion after holding up the store.