POLICE are investigating the circumstances surrounding a horror crash at Lockwood South which claimed the life of a Werribee man.
The 25-year-old was driving a ute along the Calder Alternate Highway about noon on Tuesday when he crossed onto the opposite side of the road and collided head on with a truck.
The man, the only occupant of the vehicle, died at the scene. The truck driver suffered minor injuries and experienced shock.
Acting Senior Sergeant Bruce Simpson from Bendigo Highway Patrol said an exact cause of the crash was yet to be determined but early indicators suggested fatigue had played a part.
"We have spoken to several witnesses. At the moment it is too early to establish an exact cause," Acting Senior Sergeant Simpson said.
"At this stage the indications are the deceased driver has crossed over onto the wrong side of the road."
Acting Senior Sergeant Simpson said drivers needed to take care every time they started up their vehicles.
"We can't reiterate this message enough. Just be careful on the roads," he said.
"Make sure you don't drink or drive, you pay attention to what is going on (and) you are well rested.
"And at the moment, with school holidays on, there are a lot of families on the roads and we don't want them to come into harms way."
Acting Senior Sergeant Simpson said Tuesday's crash scene was confronting for all involved.
"The amount of emergency services involved is enormous," he said.
"And the deceased is someone's family, it's distraught for everybody."
Acting Senior Sergeant Simpson said several witnesses were helping police with their investigations.
The road toll sits at 184, compared with 175 at the same time last year.
UPDATE 1.44pm: The man killed in a crash on the Calder Alternative Highway around 12pm today was 25 years old and from Werribee in Melbourne's west.
The man was driving a ute when it crossed over onto the opposite side of the road and collided with a B-double truck.
Acting Senior Sergeant Bruce Simpson said investigations into the cause were ongoing but it appeared fatigue played a part.
Acting Senior Sergeant Simpson said the driver of the B-double truck suffered minor injuries.
UPDATE 1.20pm: Bendigo Highway Patrol Acting Senior Sergeant Bruce Simpson will address the media on scene in 10 minutes.
UPDATE 1.12pm: Police are investigating the circumstances surrounding a fatal crash which occurred in Lockwood South this afternoon.
Officers believe that a car was headed south on the Calder Alternative Highway when it collided with a north bound truck.
The driver of the car, believed to be a man in his 30s, died at the scene.
The driver of the truck, believed to be a man in his 50s, is assisting police with their investigation.
Anyone who witnessed the collision is asked to contact Crime Stoppers on 1800 333 000 or to make a confidential report at www.crimestoppersvic.com.au
UPDATE 1.05pm: The collision appears to have involved a car and B-double truck.
Police media liaison will hold a press conference in relation to the incident later this afternoon.
UPDATE 12.55pm: A spokesperson from Ambulance Victoria said a male with a minor leg injury was being transported to Bendigo Health.
UPDATE 12.52pm: The SES, police, CFA and ambulance services are attending the scene of a car crash on the Calder Alternative Highway at Lockwood South.
UPDATE 12.41pm: Traffic is blocked in both directions on the Calder Alternative Highway at Lockwood South.
UPDATE 12.25pm: The Bendigo CFA has said the crash is on the Calder Alternative Highway near Old Coach Road, Lockwood South.
A spokesperson said at least three fire trucks are attending the scene.
UPDATE 12.11pm: The location of the accident is actually on the Calder Alternative Highway, Lockwood South. Emergency services are on the way.
EARLIER: Emergency services crews are on their way to a reported car crash on Marong Road, Maiden Gully.