LISA Greenwood and Andrew Storie will jump out of a plane this Saturday for the 65 Roses Challenge.
A team of seven people, the majority of them Bendigo residents, will skydive at 15,000 feet and free fall for 65 seconds.
The big jump is a fundraiser for cystic fibrosis and coincides with the end of Cystic Fibrosis Awareness Month.
Ms Greenwood is getting nervous about the skydive and says she has already had a few nightmares.
But she knows it's all for a good cause.
"Karmilya Lovett is the jump organiser she has a daughter with cystic fibrosis," Ms Greenwood said.
"Karmilya lives in Shepparton now but I actually went to school with her in Bendigo.
"She was on Facebook asking people to join her on the skydive so I got in touch."
I'd always wanted to do skydiving and then I met Sharnie and I thought what an awesome cause ...
Ms Greenwood was inspired to sign up through her links with Sharnie McDonald, a three-year-old with cystic fibrosis.
"I met Sharnie through her mum Courtney who I also went to school with," she said.
"I'd always wanted to do skydiving and then I met Sharnie and I thought what an awesome cause to do it for."
Sharni's mum Courtney Hicks said there was no cure for the cystic fibrosis.
"It's the most common genetic disease," she said.
"There's a carrier in every classroom.
Bendigo residents skydive for cystic fibrosis research
"I don't like talking about it very much but it's definitely a worthy cause."
Cystic fibrosis primarily affects the lungs and digestive system because of a malfunction in the exocrine system, responsible for producing saliva, sweat, tears and mucus.
People with CF develop an abnormal amount of excessively thick and sticky mucus within the lungs, airways and the digestive system.
All participants in the 65 Roses Challenge will pay for their own jumps with $100 from each skydive to go towards research and support for people living with cystic fibrosis.
Management and treatment of CF is lifelong, ongoing and relentless, says the Cystic Fibrosis Federation.
People with CF are not encouraged to socialise with each other. The risk of cross-infection and exacerbation of lung conditions is too great. CF can be a lonely existence.
"We're doing it through Skydive Nagambie," Ms Greenwood said.
"It's all pretty exciting and scary at the same time."
To donate or find our more visit https://65rosesvic.everydayhero.com/au/65rosesskydive