UPDATE, 10.40AM: An Ambulance Victoria spokesman said a man in his 40s was being transported to hospital.
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"He has a neck injury," he said.
"They're treating two others at the scene."
EARLIER:
Emergency services are attending a crash at Lockwood crossing on the Calder Alternate Highway.
A Toyota Landcruiser and Subaru Liberty wagon have collided.
Paramedics are treating two people from the Landcruiser but the extent of their injuries are unkown.
The occupants of the Subaru have escaped injury.
Police have blocked the Maryborough Road as emergency services work at the scene.
The Calder Alternate Highway remains open but traffic is slow.
Police, ambulance, CFA and tow trucks are at the scene.
More to come...