An elderly Bendigo woman has died after her car veered off the road and hit a tree in Archdale near Maryborough.
Investigators believe a Toyota Corolla was travelling along Archdale-Dunolly Road at about 4.15pm yesterday when the driver lost control of the car.
The car veered off the road and hit a tree.
The 84-year-old Bendigo woman and only occupant of the vehicle died at the scene.
Bendigo Highway Patrol Acting Senior Sergeant Della Nihill said the investigation was still ongoing.
"It is unknown what caused the crash at this stage," she said.
It follows a four-person fatality near Elmore on Saturday night, in what has been a horror weekend on central Victorian roads.
Police are investigating speed, alcohol and irresponsible behaviour as possible causes of the crash that claimed the lives of four central Victorian men and left three seriously injured.
The head-on collision occurred just before 10pm on Saturday on the Heathcote-Rochester Road in Burramboot.
Two teenagers were travelling south in a Holden sedan, which veered off the road and collided with a 4WD travelling in the other direction.
The 18-year-old driver from Bendigo and his 19-year-old passenger from Elmore, and a 53-year-old and 52-year-old, both from Rochester, were killed in the collision.
A 21-year-old is fighting for his life at the Alfred Hospital, an 18-year-old is in a serious but stable condition at the Royal Melbourne Hospital and a 28-year-old sustained minor injuries and remains at the Bendigo Hospital.