The top-of-the-ladder Spirit (10-1) will ride a 10-game winning streak into Saturday afternoon's clash with the third-placed Boomers at the State Basketball Centre.

The Spirit are dominating the opposition at both ends of the floor, with their average winning margin in their 10 victories 17 points.

The Boomers (8-3) are also shaping up well, with Molloy relishing the opportunity for his young side to take on the defending champions.

The ladder positions of the two teams, coupled with the game being televised live on ABC TV, gives the clash blockbuster status, but the Boomers are taking a low-key approach to the WNBL's toughest assignment.

"We've been fairly low key this week. I've got a very young team and we're probably on a different journey to Bendigo at the moment in just trying to establish ourselves," Molloy said on Thursday.

"Coming up against the side that is clearly the No.1 team in the league and the reigning champions is exciting.  We know the quality of the opposition is going to be very high."

Melbourne is coming off a mixed two games last weekend, defeating Adelaide by 14 points and losing to Dandenong by 15 points.

The Boomers side includes former Spirit players Hayley Munro, who was part of last season’s championship team, and Tess Madgen.

While the Spirit will take on two former players on Saturday, they won’t have to contend with the Boomers’  injured franchise player Rachel Jarry, who hasn’t played for Melbourne since October 25.

“We know Bendigo is going to be a very difficult opponent, and they have some players in ominous form,” Molloy said.

“They are certainly deserving of their status as the No.1 team right now.”

Saturday’s game tips off at 3pm in what will be the second week in a row the Spirit - who defeated Adelaide by 13 points last Saturday -  have been televised live on ABC TV.