THE Rolling Stones concert is estimated to inject up to $3.5 million to the regional economy.
Macedon Ranges Mayor Roger Jukes said the concert at Hanging Rock on March 30 was a "coup" for the region.
"It is a major economic boost," he said.
"Not just because The Rolling Stones are an international act who will draw in a huge audience, but also because we can continue to build on our ability to show off Hanging Rock."
Cr Jukes said he expected people who had never been to Hanging Rock to visit to see The Rolling Stones.
"We expect those people will come back to visit the region in the future.
"There will be long-term economic benefits from this event."
City of Greater Bendigo city futures director Stan Liacos said not all benefits could be quantifiable
"There are obvious goods and services that will be supplied by businesses in the region," he said.
"But there are also benefits that you cannot measure, such as reputation.
"The concert will provide the Greater Bendigo region with the opportunity to promote itself well into the future.
"We have been on a journey to ensure Bendigo has a positive reputation in Victoria.
"This will reinforce the public perception we have worked to develop."
This event is not the first time the region has received an economic boost from an international act performing at Hanging Rock.
Bruce Springsteen performed in March for two nights, which brought in about $9 million for the Macedon Ranges region, with an estimated 17,000 people attending the concerts.
Hedges Farm in Carlsruhe owner-operator Suzi Seers said she could have booked her accommodation 20 times over when Springsteen performed.
"We expect there will be a similar demand for accomodation," she said.