The head-on crash happened near the intersection of Williamson Street about 3.30pm.

One car was written off after it attempted to turn into the carpark beside the Bendigo Law Courts. 

Bendigo police attended and helped move the second car away from traffic.

In a separate crash in Harcourt, two people were taken to hospital after their car collided with a truck this afternoon.

The car was attempting to turn onto the Old Calder Freeway but failed to give way.

Castlemaine police attended and blocked traffic near the intersection of Twyford Street for more than an hour and a half.

The road was reopened about 4.15pm.

Police said the driver and passenger in the car were lucky to escape with minor cuts and bruises.

The truck driver was uninjured.